CDC Notifies States, Large Cities To Prepare For Vaccine Distribution As Soon As Late October

[Colleen27]

So you suspect rapid testing might be involved in DLR reopening?

It is all speculation at this point. Until we see the actual official guidance from California, I wouldn't even hazard a guess as to if or when DLR will reopen in the foreseeable future - the rumors suggest the reopening guidance may create a situation where it doesn't make financial sense to do so, but that is only rumor at this point. But the SNL thing does at least raise the question of whether rapid tests might be used for one-day events where all that really matters is whether someone is positive enough to be contagious at a particular point in time.

 

[godisney14]

It is all speculation at this point. Until we see the actual official guidance from California, I wouldn't even hazard a guess as to if or when DLR will reopen in the foreseeable future - the rumors suggest the reopening guidance may create a situation where it doesn't make financial sense to do so, but that is only rumor at this point. But the SNL thing does at least raise the question of whether rapid tests might be used for one-day events where all that really matters is whether someone is positive enough to be contagious at a particular point in time.

You can be contagious even with a negative rapid test.

 

[Colleen27]

You can be contagious even with a negative rapid test.

My understanding is that they're quite effective, though of course not perfect, at screening out those with a substantial viral load. I know there's still a great deal of uncertainty about where the contagion threshold is, but there's also a lot of optimism that the less sensitive rapid tests are accurate enough to screen out those in the active phase of the virus and therefore greatly reduce the chances of a contagious person being admitted (compared to temp screenings and other measures currently in use, not as a replacement for masks and other precautions).

 

[mousefan73]

This is my opinion on testing and Covid: nothing is 100% safe, accurate or preventable, but we need to somehow move on smartly.

 

[Pyotr]

This is my opinion on testing and Covid: nothing is 100% safe, accurate or preventable, but we need to somehow move on smartly.View attachment 530199

I’m going to have nightmares from that cow. Thank you.

 

[BrianL]

I’m going to have nightmares from that cow. Thank you.

Remember what Troy McClure said: "Don't kid yourself, Jimmy. If a cow ever got the chance, he'd eat you and everyone you care about!"

 

[godisney14]

My understanding is that they're quite effective, though of course not perfect, at screening out those with a substantial viral load. I know there's still a great deal of uncertainty about where the contagion threshold is, but there's also a lot of optimism that the less sensitive rapid tests are accurate enough to screen out those in the active phase of the virus and therefore greatly reduce the chances of a contagious person being admitted (compared to temp screenings and other measures currently in use, not as a replacement for masks and other precautions).

There are no tests that is 100% perfect (precision and accuracy), some are close but not 100.000000%.

With that said, SARS-COV-2 rapid tests in question are new but still more specific and effective in screening than taking temps. That's a given. But, the window of opportunity to get a reliable result with these rapid tests is relatively narrow (according to the manufacturer specs).

And, there's no such thing as screening out contagious people. Rapid test results do not report the viral load of a sample. Based on the test design specs, they can only report a binary result, positive or negative, relative to a pre-determined viral load threshold. The thing is, no one yet knows what the minimum infectious dose is with this virus. Most estimates in literature that I have seen point to a level that is lower than the sensitivity levels of these rapid tests. That is a design decision of the test.

The question is: Do people in charge of various organizations making the decision of whether to test, and which test to use, deem false positives or false negatives to be the lesser evil?

 

[RamblingMad]

This is my opinion on testing and Covid: nothing is 100% safe, accurate or preventable, but we need to somehow move on smartly.View attachment 530199

Cows kill a lot of people. Look it up. You’ll be shocked.

 

[aggiedog]

https://www.nytimes.com/2020/10/05/us/politics/coronavirus-vaccine-guidelines.html

 

[mousefan73]

https://www.nytimes.com/2020/10/05/us/politics/coronavirus-vaccine-guidelines.html

Isn’t the first step having ex Pfizer review and release their data? This is a bit off still per my understanding ?? Pfizer themselves say very end of October - maybe.

 

[aggiedog]

One of the sticking points is the FDA wants a median of 2 months of data after the second dose before looking at the safety. Supposedly that will put it firmly past the election. The article goes on to say that the drug companies may just ignore the WH anyways.

 

[brent02139]

One of the sticking points is the FDA wants a median of 2 months of data after the second dose before looking at the safety. Supposedly that will put it firmly past the election. The article goes on to say that the drug companies may just ignore the WH anyways.

trump already says vaccine for everyone by April and scientists/doctors says it'll be later. So even the rosy picture is April when things goes back to normal
https://www.cnn.com/2020/09/18/health/trump-coronavirus-vaccine-april-promise-bn/index.htmlI think that's the closest we'll get to a prediction before FDA goes through the review process.

 

[Jonfw2]

You can be contagious even with a negative rapid test.

Right now, you can walk right into WDW with just a temp check. Which is more accurate?

 

[Jonfw2]

In the wake of Trump getting Regeneron's antibody drug, Eli Lilly has filed for emergency use approval of theirs...the floodgates are opening.

EDIT: they plan to have 1 million doses available by the end of the year.

https://www.thestreet.com/investing/eli-lilly-files-emergency-use-application-for-covid-antibody

 

[okeydokey]

I wonder if Eli Lilly's treatment also uses embryonic stem cells like in Regeneron. Some folks may prefer the non-embryonic cell treatment for this reason. It will be interesting to see how this plays out.

 

[FlightlessDuck]

See, this is why you never give dates when you talk about timelines. They always slip.

 

[FlightlessDuck]

https://www.nytimes.com/2020/10/05/us/politics/coronavirus-vaccine-guidelines.html

"the White House chief of staff objected to provisions that would push approval past Election Day. "

What a shock. I'm flabbergasted. Truly gobsmacked.

 

[Jonfw2]

I wonder if Eli Lilly's treatment also uses embryonic stem cells like in Regeneron. Some folks may prefer the non-embryonic cell treatment for this reason. It will be interesting to see how this plays out.

Good question. To clarify, Regeneron is not using the stem cells from actual aborted fetuses. They are using stem cells from lab-created sources. Although, I realize that many people would ethically still look at that process as a conception taking place.

 

[Jonfw2]

See, this is why you never give dates when you talk about timelines. They always slip.

Actually, these antibody drug EUA's are exactly along the lines of what was predicted months ago.

 

[RamblingMad]

"the White House chief of staff objected to provisions that would push approval past Election Day. "

What a shock. I'm flabbergasted. Truly gobsmacked.

I want a helicopter to land on my front lawn and take me to the hospital if I get COVID. I then want all of the experimental stuff too.