I know a good amount about bed bugs. The first thing to realize is they only need to eat once a year to stay alive; however fabric and batting material is their preferred location.
Since my husband travels internationally, sometimes to some seriously poor countries, we have a whole routine.
You can purchase things that kill bed bugs if it will make you feel better--you can spray them with some chemicals, just google.
We "treat" his luggage with temperature every time he goes somewhere questionable. He is not afraid of his hotels--since he checks the rooms--he is afraid of the other luggage in the under belly of the plane on trips.
We live in IL--so if it is winter--his suitcase and all of his possessions remain in the garage in garbage bags for one week. It gets cold enough to kill anything.
If it is summer we put all his stuff into a giant fake suitcase with a heater--it heats up to like 125 degrees which is enough to kill bed bugs. With dozens of trips to horrible places our home has never been infected--we have found a few dead bugs in the "treatment suitcase thing".
Following the heat or cold treatment weather dependent, I then sort his clothes in the garage and walk loads directly to the washing machine. It may sound a little nutty--but it is better than having to treat my whole house or have a cat with bed bugs.