Not the OP but we stayed at Times Square Suites for 4 nights this summer before our Alaska cruise. We absolutely loved the hotel but it does have some things to consider.
1) Depending on where your room is at, it is noisy. We knew this going in and we usually sleep with ear plugs anyway so it was not an issue for us. Our room faced the back of the hotel and the only time we really heard any noise was from the trash trucks. But I heard some of the rooms facing the front can get noise from the streets below.
2) Depending on where your room is at, the view is not so great. Again, our room faced the back alley and there was no view at all (unless you like driveway and trashcans, lol).
But for us, the pros definitely outweighed the cons. The room was huge (like an apartment) and it was great having a separate sleeping area for the parents and kids. We were there in August and the A/C in the main bedroom was nice but there were also fans in all the other rooms. We never found it uncomfortably warm, even though it was in the 80s every day we were there.
We enjoyed the roof-top patio area and the location was super convenient to Stanley Park, the waterfront, tons of restaurants and even a Safeway across the street to stock up the room.
It was great being able to have meals in our room (definitely saved over eating out three meals a day for 4 days) and we did a few loads of laundry the night before the cruise, which helped with being able to pack fewer clothes.
We loved Times Square and Vancouver so much that DH wanted to plan another trip back to Vancouver and stay there again, just to have more time checking out the sights
We stayed at the Pan Pacific for two nights before our Alaska cruise in 2014 and while we loved the location and view there, I would not have wanted to stay there any longer than we did. They only had double beds, which made 4 people sharing two beds really tight. And there wasn't even a refrigerator in the room to keep drinks cold. So when we stayed there, all our meals were eaten out, which just added to the price.