The only problem with calling the Front Desk is that you are calling a call center, and it may take more than 1 hour for you to get any attention to your issue.
@Ricguz suggestion to actually visit the Front Desk it the way to go but
@tkmking they are hesitant to disturb the Guest(s) making noise unless it is an obvious nuisance. The will often offer to move you to another room as the first option.
Are they just noisy entering, and leaving the room or is it loud conversations, TV noise or something else?
Dave