Hi... we just did this on the 19th of July ( a week ago ). We took the train into Union Station from Anaheim then the red line subway right to Hollywood/Highland metro station. WAS VERY EASY. I had driven from Santa Monica to the Grove/Farmers Market then Anaheim the week before and driving was miserable. Anyway, the metro stop at Hollywood & Highland has everything.... At that stop is the walk of fame, Chinese theater and if you go to into the Kodak Theatre shopping area, to the 3rd or 4th bridge, PERFECT view (and free) of the Hollywood Sign.
How old is your granddaughter? Startours has alot of tours that leave from there- there is a 2 hr hop on/off tour that brings you different places around the city- The Grove/Farmer's Market is a nice place to stop and shop and have lunch (Farmer's Market is cheaper and lots of options). We did the TMZ tour around town... got to see the highlights of La with a twist- like stores in Rodeo drive that so & so shops at, lots of gossip, dirt, ect. My 17 yr old loved it.... I enjoyed it way more than I thought I would.... The general opinion I kept getting was that tours of "the stars homes" was just a waste of time and money. Only saw long driveways or hedges. Maybe someone knows of a tour that shows more but I didn't find one.
If you drive in, there is parking at both the Grove and at Hollywood & Highland. Reasonable costs.