Where are you going?Disney,Universal,Downtown etc...If going to Disney take the Turnpike to exit 267 which is route 429 which is a new expressway that has little to no traffic,take that south to exit 8 which is Western Way which will lead you to Buena Vista dr by the Coronado Springs.If going to say Universal or the International Drive area just take the Turnpike to I-4 which is exit 259 and go west towards Tampa,Universal and I-Drive will be about a mile away.If going to Downtown Orlando then you would go east on I-4 towards Orlando.