Great thread! This is just what I was looking for. We'll be driving from Yosemite area so should we just drop off the car rental? We'll be flying home from San Fran area.
What hotel would you recommend? We like to be close to where the main tourist attractions are but also in a safe neighborhood. Are there any areas we should avoid? Looking for a Hilton/Hyatt type. We'll only have 2-3 nts.
Any tips would be appreciated.

I'm just starting my research and feeling lost.