Well..... I would have to say a conditional yes. My scrapping area is set up in our master bedroom. It is a very large room and my scrapping stuff does not interfere at all. Our room has a jog that juts out over the stairwell, so that jog is where I have a large bookshelf with photo storage boxes that have my embellishments sorted by theme "Sports/School", "Halloween/Fall", "Spring/Easter" etc, etc., as well as a large stack of those 12x12 three-drawer sterile units (about 15 drawers total), that hold my rubber stamps, Disney embellishments (too many to fit in a photo box

), misc. embellishments, punches, rub-ons, etc. The jog also keeps most of the stuff out of direct sight (unless you are lying in my bed). My scrapping area is a gate-leg table that is flanked on the left by a large three drawer rolling cart that holds my scraps, larger punches, and Sizzix, with all of my solid cardstock sitting on top, sort in this Priority Mail boxes (thanks to a suggestion from someone here!). I also have another large 3 drawer rolling cart right outside the jog area (next to my TV cabinet), and a rolling kitchen cart with metal baskets that ends up holding a bunch of miscellaneous junk that I don't know what else to do with.
Overall my space works well for me, everything is right together, within a step or two. Also my TV is right there and my kids can be nearby if they want. We do have a home office on the first floor that I could move to if I wanted, but it would be a bit cramped with our current large desk. We also have a fully finished room in the basement that I could use, as it is not being used right now (it was going to be a second home office), but I don't really feel the need right now to move there.... maybe in the future. Plus I would have to be diligent about running the dehumidifier if I stored paper down there. Also, the playroom is very large and mostly unused, so I could really consider moving there. Someday I probably will. It is a great room with lots of sunlight, lots of space, etc. It's a shame the only people who see it are the kids and their friends!
Anyhow, that is my run-on answer to your question!..................P