If you need O2 on the plane, you can either get it from the airline, at quite a hefty charge, or you can take a portable oxygen concentrator with you on the plane.(POC) Your O2 supplier should be able to help you with that. Check with your airline to see what is allowed. Make sure you have enough batteries for if the flight is delayed. Once you get to your destination, it's another ball game. Your O2 provider should be able to help you as well here. Since O2 is a prescription item, they will have the prescription and can give it to the O2 provider at your destination. They will give you the name of a reliable company to deal with. Just let them know what your needs will be- concentrator for the room, cylinders for when at the parks, tubing, etc. It can be quite stressful, but I find people are usually quite helpful. You need to find out if the company you deal with at home has a branch where you are going. If not, you will have to call another. I use Lincare in Orlando, and find them very good.