I have a Nook, and I love it.
The only time I will purchase a real book, is if it's a book with tons of pictures, like a travel guide. I've also found that I don't care for reading my magazines on my iPad. I used to devour my People and Us every Friday when they arrived. Now I find that I'm about two months behind reading them.
So, I guess book, no... I don't miss real books in the least. Magazines, yes. I'd rather read a magazine in paper form.