If smoke will be that much of a negative issue for you, AND if no one in your party has a mobility impairment, then you're better off just NOT requesting Building 4. That's my recommendation to you.
It's tough to get across just how compact POFQ is. Take a look at the map below. Look for Building 2. Now go up Building 2 towards the river, and follow the building around to that "arm" that goes off to the right on the river end of the building. That's where my room was, on the 3rd floor.
From that point, including taking the stairs or elevator, it took me exactly 2 minutes to walk to the food court.

I hope that helps illustrate for you how small and convenient POFQ is.
By contrast, my room in a preferred location building at CBR was a 5 minute walk to the food court, and like I said, that was from one of the CLOSEST rooms.
And yes, I actually DID time these walks and write them down, just for situations like this!