mtblujeans said:
Has anyone else tried this? It's Phenylephrine HCI 10mg.....and Sudafed is Pseudoephedrine Hydrochloride 30mg.
Montana has such a bad Meth problem that some of the stores are no longer carrying Sudafed but will now be selling Sudafed PE that does not have the element in it that people use to make Meth.
DS and I tried it this weekend and it upset our stomachs and made us both feel woozy in the head....I would not feel safe driving after taking it. I had to go back to
Walmart and get the regular Sudafed for future use.
Anyone else notice feeling poorly after trying Sudafed PE?
This is not quite what you are saking but here goes... I was taking Dayquil which contains Psuedoephedrine Hydrochloride, when I had my stroke.. Of course I have other issues,but my doc did say that anyone with heart/BP problems should be very careful taking anything with that stuff in it... There were some strokes associated with a similar OTC drug that used something similar (PPA) and it was pulled off the market for a while
A study
Stroke Associated With Sympathomimetics Contained in Over-the-Counter Cough and Cold Drugs
Carlos Cantu, MD, MSc; Antonio Arauz, MD, MSc; Luis M. Murillo-Bonilla, MD; Mario López, MD Fernando Barinagarrementeria, MD
From the Stroke Clinic, National Institute of Neurology and Neurosurgery, Tlalpan, Mexico.
Correspondence to Carlos Cantu, MD, Stroke Clinic, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Tlalpan, Mexico City, DF Mexico PC 14269. E-mail
carloscantu_brito@hotmail.com
Background and Purpose Phenylpropanolamine (PPA) and pseudoephedrine are sympathomimetics contained in over-the-counter cold preparations. A case-control study linked PPA use with hemorrhagic stroke in women. Twenty-two patients with stroke associated with use of these drugs are described.
Methods In a consecutive stroke registry since 1988, 22 patients had stroke associated with over-the-counter sympathomimetics. Sympathomimetic dosage and type, time interval until stroke onset, and neuroimaging findings are described.
Results Ten male and 12 female patients were included. Intracerebral hemorrhage occurred in 17 patients, subarachnoid hemorrhage in 4, and ischemic stroke in 1. Stroke was associated with PPA use in 16 patients (dose 75 to 675 mg), with pseudoephedrine in 4 (dose 60 to 300 mg), and with others administered by the nasal route in 2 (oxymetazoline and phenylephrine). Stroke occurred after a single dose in 17 patients and after daily use during several days in 5. The interval between drug exposure and clinical onset varied from 30 minutes to 24 hours. Stroke occurred after recommended doses of PPA (50 to 75 mg) in 32% and pseudoephedrine (60 mg) in 50% of patients. Eight patients had acute hypertension at stroke onset. Cerebral angiography was normal in 8 cases and showed diffuse vasospasm or beading in 10 patients.
Conclusions Stroke related to over-the-counter sympathomimetics was associated with acute hypertension and/or vasospasm or angiitis mechanisms, most related to the use of PPA; however, stroke also occurred with the use of other sympathomimetics, particularly pseudoephedrine. Although stroke complications occurred when doses were used that were higher than recommended doses, apparently there is also a stroke risk when these agents are taken properly.
