I had my last child at 43. My system never went back to normal. The reason....menopause!! Went on HRT. Worked like a charm. I was no longer a 'loon'. Well. My mother was diagnosed with breast cancer. Seems it's a real family trait. So, I stop HRT. That's when the hot flashes, sleeplessness, etc. started. My obgyn put me on Sarafem. Said he wasn't sure if I was depressed due to lack of sleep or not sleeping due to depression!! I had to stop the Sarafem. I just couldn't function the next day. He says it evidently works for quite a lot of women tho. It also upset my stomach something awful. Felt nausous all day. It was just like having morning sickness. Now I take Ambien for sleeping. It's a miracle drug in my opinion. If the Sarafem works for you, then stick with it. It's too bad there seems to be a stigma attached to these drugs. If you have hight blood pressure you take meds, right? It's an imbalance in your system. So fix it!