sure - they are nice and thick to hold(better for the characters fluffy, chunky hands to handle) but be sure that your autograph book has thick pages as the sharpies might bleed thru the paper.
We used sharpies last year when my niece was having the characters sign her hat and they worked great! The only problem was the characters would sign her sister's autograph book with them and they went through the next few pages. I would avoid the sharpies unless the book has thick pages (unlike the WDW autograph books). Have a great time!
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