I wouldn't do it. I've been to the Disney outlet that was in Hilton Head (closed years back) and the Orlando Premium Outlet. Didn't find a thing in either that I wanted or needed. If you happened to be in Myrtle Beach on vacation, that would be one thing....but just driving there to shop, hoping to find some deals? Nope.
I wouldn't make that drive either. I live under 30 minutes from the outlets and shop there often. DD13 and I sometimes walk in the Disney store "just because". I can't tell you the last time we bought anything. The last few years it's been mostly stuff for small kids like cups, toys, some costumes. The adult T-shirts are ho-hum, not a big selection.
Funny thing is, we go to Broadway at the Beach to shop and get more "Disney Feeling" there. It reminds us of DTD in some sections.