I would say MORE than two days of driving.
We're an hour away from you and when we drive to NORTHERN CALIFORNIA it is a two day driving trip. We've also driven NoCal to DL and it's a SOLID DAY of driving, so I would plan on THREE days of 8-10 hour driving.
BTW...we just passed thru ML couple days ago on the way to a tournament...unbelievable all the new housing! Waving hi!