Your home resort matters because you can make reservations there 11 months before your trip. You can make reservations at other
DVC resorts 7 months before your trip.
If you primarily want to stay at the smaller resorts, such as BCV, VWL, or BWV, it can be very difficult to get reservations at 7 months out, at certain times of the year (early Dec., during the F&W festival, etc), since the owners at those resorts have booked at 11 months.
Since OKW and SSR are so much larger (and therefore have many, many more villas), it's generally easier to get the reservation you want at 7 months.
So, if you really don't care where you stay, or if you prefer staying at SSR or OKW, then your choice of home resort doesn't matter so much.
If work or school constraints prevent you from planning a trip more than 7 months ahead of time, then it doesn't make much difference where you'll buy, as you won't be able to use the 4-month head start at your home resort.
Also, take a look at the maintenance fees. They vary by resort, and you may want to figure that into your purchase decision. For instance, you'll probably see a bunch of VB resales out there, with attractive prices. But VB has the highest maintenance fees of any DVC resort, so any savings you got on the purchase price would quickly be eaten up by the fees.