Oooh....my first thought was a 2br at VWL or the Yellowstone suite.
But we love Wilderness Lodge and I know it's in our future plans for quite some time. So in that case I'd pick the largest room/suite at the Poly on concierge with a lagoon view.
My first choice would be Tower Room, Magic Kingdom view at the Contemporary. Second would be a Magic Kingdom view room at the Polynesian. Third would be Epcot view room at the Beach Club.