There is usually a kiosk in our mall that sells personalized ornaments with the year on them. We've gotten these for several people in the past. We make sure that we not only put the human's names on them, but the pets' names, too.
We also give wine as gifts. If a friend of mine gets a bottle of wine from us, they know that I've done my homework on it and have paired the wine to their known likes. Of course, it also helps if the recipient is also an oenophile, or even a wanna-be oenophile (lover of wines.)
Holiday-themed serving bowls or platters or candle sticks are also easy and nice things to give a couple, or even a set of those fancy swirly candles to put in the candlesticks they already have.
Now, if my DH's cousin, Carmen, and his wife are friends with you... his and hers harley t-shirts are always appreciated, especially if you go online and buy them from a dealer in another state.