Well, here's my opinion:
We built a home here two years ago, moving here from Pennsylvania. The only thing I really really miss is my basement where I could store stuff like xmas decorations, luggage, our second refrigerator, our freezer, everything that people put in basements. Oh, and the cat litter box too. Now the two litter boxes are in the laundry room which is the normal size laundry room in most houses and between the washer, dryer and litter boxes, you can barely walk thru it into the garage. Then of course the cats track the litter into the kitchen, etc. We have a two car garage which we actually keep our two cars in (barely) plus the second refrigerator and our upright freezer. We also went with a fourth bedroom for storage but in all honesty I would have preferred a three car garage, a super huge laundry room besides the fourth bedroom. So in order of preference, if I had to do it over again, this is what I consider the most important:
(1) super large laundry room to hold litter boxes, washer, dryer, all cleaning supplies, second refrigerator and upright freezer.
(2) three car garage to hold two cars and lawn mower, ladders, usual garage stuff like bikes, etc.
(3) although we have it already, you definitely want a guest bedroom with it's own bathroom because you will have loads of guests if you are living near Disney World and having to keep the kids' bathroom nice enough (remove the toys, or in case of a teenager, all their makeup and beauty supplies) for guests to use too is super hard! We are soooo glad we built four bedrooms (although one is used strictly as storage) and three full baths because who knew we'd get so many guests!!!!
Hope that helped.