I can't speak to Orlando specifically....I wish I could, because we rely heavily on Uber when down there. However, we were just in Ft. Myers and got a Uber twice with NO problem. Our driver (for what it is worth) during our second drive told us there had been a real uptick in folks requesting rides. First driver hardly spoke, he and we wore masks. Second driver was very friendly, he and we both wore masks. Second driver told us Uber required drivers to wear masks.
It's easy to get a idea of costs, by going on their websites and putting in a sample ride.
I'll be following along, hopefully someone with better knowledge will chime in!