You didnt say how many people would be with you. We found that if we had more than 3 people it was cheaper to hire a car service to take us to the port than to use the Disney transfers not to mention you can decide when to leave and you are on your own schedule not that of the Cruiseline itself. Also depending on what time you are due to arrive in Orlando would be a big factor to me on where I stayed. If you get in early morning maybe get a WDW hotel and go to Disney for the day. If you arrive mid-afternoon get a car service and head to the Port area and if you arrive at night I'd stay at the Hyatt and leave for the port the next morning. I would think it is all a matter of preference to you. We HATE trying to figure out how to drive where we are going so we get a car service to take us. Some people drive to the port (it's about an hour away) and stay the night at the Radisson on somewhere nearby so they can be close on the embarkation morning. We go down a few days early (just to be safe and not chance missing the cruise) so we stay at a WDW property with the kids. I dont know if I would like to have to drive to the Port area at night after flying but that's just me.
Heidi