I've drivin from Kenosha, Wisconsin 3 times. We usually try to drive straight through, but usually end up stopping at a rest stop in chattanooga for a couple hours.
We always left after work (because we wanted to get there as soon as we could!) and we didn't wan to wait until the next day. But this next time we will be leaving around 4 or 5 in the morning, so that most of our driving will be during the day. It's hard to drive all night long!!!
Have fun!!!
I would MUCH rather drive than fly, it's so much fun to go to and see different parts of the united states. I love drivng throughthe smokeys!