I would call the gardens 407-246-2620
they are in downtown Orlando (1920 North Forest Avenue) - not really near WDW or SW or IOA/US.
I4 - exit 85 - to Princeton Ave, south on Mills Ave,then .5 mile east Virginia Dr.
there is a Comfort Suites Downtown - I4 exit 85 - 2416 N Orange Avenue
there are several at exit 84 - Best Western Orlando West, Holiday Inn Orlando Downtown, Orlando Marriott Downtown, Travelodge Colonial Plaza.