I like to saute tilapia in a sprayed pan. Once the "second side" is almost done after flipping, I"ll add a little butter or soy-free margarine, garlic and lime juice to the pan to make a little bit of a sauce.
If you take out the lime, but add diced tomato and nicoise (or any, really) olives you've got a dish that's excellent with couscous or rice.
Sometimes I'll make a rub of cumin, turmeric, and garlic and saute it that way. Served with rice it has a kind of Indian flair.
ETA: my son's fave: sauteed plain in butter or margarine, when almost cooked through add in a bit more butter, a bit of chicken or veg broth or coconut milk (amount depends on how many you're feeding and how much sauce you want), some Thai red curry paste and any leftover (pre-cooked) veggies you've got around - we like broccoli or carrots and onions. Warm through and serve over rice noodles.
You can also dip tilapia and egg and bread it (I use rice or corn crumbs, but nuts, cracker crumbs, bread crumbs or plain old flour ETA: or sesame seeds, toasted or not) and saute it in the barest butter or oil. Then cut it up and serve in tortillas with cheese, lettuce or slaw, and salsa for a (slightly) healthier and not-quite-authentic fish taco.
Can you tell we eat a good amount of tilapia around here? It's my go-to for when we're running late or no one feels like doing much. It thaws in a snap in a pan of warm water right out of the sink and I've even been known not to bother with thawing at all - just plop it right in the pan. So versatile and fast!