Do you mean the type where all the extra spaces on a page are filled with square, or rectangles of different colors? If so, here is what I do.
First I choose at least 3 papers that go with my pix, 2 solid, 1 print or 3 solids.
Then I crop all the photos into some sort of square shape or rectangle. I lay them out on the page, staggering them here and there so that they don't all line up. Then I mat a few of them, and fill in around them with other pieces of cardstock that fits in the holes. Be sure to keep any vertical or horizontal lines that are supposed to line up , lined up. Add a second color or shape to your little extra spots, or a sticker, button, fiber etc. You can journal in them too. Gosh I hope this makes sence. Also hope its what your looking for.
I use colorblocking when I have a lot of photos of different things, like when we are in Mexico and I take a bizillion pictures of the flowers and animals. This way the page doesnt have to be a theme, just a mixture of fun pics.
What ever you do it will be great. Everyone does it a bit differently.