CDC Notifies States, Large Cities To Prepare For Vaccine Distribution As Soon As Late October

[dvcgirl67]

He literally says in this piece that it’s going to be free.

and if you can show where I said it’s a cure, please do so.

I’m truly baffled as to why you’re so against this. I assume it’s because you don’t like trump, but I really don’t get it.

I'm not against any therapeutics that may help to save people. I'm 100% for them. I'm against seeing these drugs being spun for political purposes so close to an election, by people who sound like used car salesmen.

I'm against someone telling the American people that COVID is no big deal, because if you get it, you simply go to the hospital, get this drug, and you're all better. As if that's something that can happen...for everyone. Regeneron currently has 100K doses of this drug, and it still has not gotten EUA from the FDA.

We're back up into the 50K range for daily cases, with nearly 1000 people a day who are dying. Hospitalizations are going up. All of those trends are going to go up at we get further into the fall and into winter. Let's hope Regeneron starts doling out this medication quickly. Because again, I just heard the other day that "all seniors will get this drug if they need it, and it will be free, and they will be cured." If that's true....then let's see it happen.

https://www.cnbc.com/2020/10/09/dr-...irus-antibody-drugs-wont-end-us-epidemic.html

 

[Jonfw2]

I'm not against any therapeutics that may help to save people. I'm 100% for them. I'm against seeing these drugs being spun for political purposes so close to an election, by people who sound like used car salesmen.

I'm against someone telling the American people that COVID is no big deal, because if you get it, you simply go to the hospital, get this drug, and you're all better. As if that's something that can happen...for everyone. Regeneron currently has 100K doses of this drug, and it still has not gotten EUA from the FDA.

We're back up into the 50K range for daily cases, with nearly 1000 people a day who are dying. Hospitalizations are going up. All of those trends are going to go up at we get further into the fall and into winter. Let's hope Regeneron starts doling out this medication quickly. Because again, I just heard the other day that "all seniors will get this drug if they need it, and it will be free, and they will be cured." If that's true....then let's see it happen.

https://www.cnbc.com/2020/10/09/dr-...irus-antibody-drugs-wont-end-us-epidemic.html

The 7 day moving average for deaths is around 720. But I don't disagree with you on the political aspect. Meaning, Trump's words don't help.

One important thing to remember with these antibody treatments is that not everyone who tests positive will need them. People who are able to develop their own antibodies early on in their infection period will not need this drug- that substantially reduces the amount of people who will need it, increasing the amount of at-risk people who will have access to it.

 

[mousefan73]

I am curious who decides and what the deciding factors are on who gets this.

 

[dvcgirl67]

The 7 day moving average for deaths is around 720. But I don't disagree with you on the political aspect. Meaning, Trump's words don't help.

One important thing to remember with these antibody treatments is that not everyone who tests positive will need them. People who are able to develop their own antibodies early on in their infection period will not need this drug- that substantially reduces the amount of people who will need it, increasing the amount of at-risk people who will have access to it.

Yes, I understand how the treatment works. I was a critical care nurse for years, so understand the science behind it.

 

[Jonfw2]

I am curious who decides and what the deciding factors are on who gets this.

According to the COVID Tracking Project, around 35,000 people are currently hospitalized in the US. Why not just start with all of them?

https://covidtracking.com/data

 

[ford family]

You’re absolutely correct. The Oxford/AZ work is phenomenal. Both vaccine and treatment. No doubt.
But to be fair, the US is paying for almost the entire thing.

How philanthropic of you.
Any connection between any advance payment and obtaining vaccine/antibody test doses when available?
Maybe the rest of us, UK, EU, Switzerland, Japan, Australia, Israel etc etc are getting them for free?
No, thought not.

ford family

 

[Jonfw2]

How philanthropic of you.
Any connection between any advance payment and obtaining vaccine/antibody test doses when available?
Maybe the rest of us, UK, EU, Switzerland, Japan, Australia, Israel etc etc are getting them for free?
No, thought not.

ford family

Not sure what you're looking for here- the US is underwriting this study. It just is.

 

[aggiedog]

According to the COVID Tracking Project, around 35,000 people are currently hospitalized in the US. Why not just start with all of them?

https://covidtracking.com/data

Simply being hospitalized is not an indication for any given treatment. Clinical status and specific diagnoses are what indicate which treatment is most likely to be beneficial. Even that is a moving target as we get more good, reproducible data on what is effective for all the variants of this disease.

 

[ford family]

Not sure what you're looking for here- the US is underwriting this study. It just is.

The US study or everything?

ford family

 

[Jonfw2]

The US study or everything?

ford family

The UK gave them 131 million pounds. The US gave them 1 billion American dollars. Make of that what you will.

https://www.biospace.com/article/u-...eca-more-than-1-billion-for-covid-19-vaccine/

 

[Jonfw2]

Simply being hospitalized is not an indication for any given treatment. Clinical status and specific diagnoses are what indicate which treatment is most likely to be beneficial. Even that is a moving target as we get more good, reproducible data on what is effective for all the variants of this disease.

My understanding is that people who are unable to quickly produce their own natural antibodies are the cases that are more likely to progress into moderate and severe- is that accurate?

 

[ford family]

The UK gave them 131 million pounds. The US gave them 1 billion American dollars. Make of that what you will.

https://www.biospace.com/article/u-...eca-more-than-1-billion-for-covid-19-vaccine/

Because you need a lot more doses?

The EU countries have paid Astrazeneca1.25 billion US dollars so far.
Japan has paid for 120 million doses
Trials are continuing in Brazil, India, Japan and other countries.

The UK has similarly bought into Covid19 vaccine programmes from US companies such as Novavax and Johnson & Johnson.

There is a global effort to find an effective vaccine within which the US is heavily involved.
As for your statement with regard to the AZ/Oxford programme "the US is paying for almost the entire thing" you are hugely overreaching.

ford family

 

[godisney14]

Not sure what you're looking for here- the US is underwriting this study. It just is.

What exactly do you mean by “the US is underwriting the study?” Pretty vague.

 

[dvcgirl67]

The UK gave them 131 million pounds. The US gave them 1 billion American dollars. Make of that what you will.

https://www.biospace.com/article/u-...eca-more-than-1-billion-for-covid-19-vaccine/

Every country is simply spending billions and billions to buy vaccines. The EU purchased and is getting 400 million doses of the AZ vaccine. Plenty of countries around the world are spending big, big money on vaccines. The U.S. is not unique in this regard.

We are a great spot to set up a vaccine trial though....so many infected people roaming around....which is not great, but hey, it is what it is right?

 

[Jonfw2]

Because you need a lot more doses?

The EU countries have paid Astrazeneca1.25 billion US dollars so far.
Japan has paid for 120 million doses
Trials are continuing in Brazil, India, Japan and other countries.

The UK has similarly bought into Covid19 vaccine programmes from US companies such as Novavax and Johnson & Johnson.

There is a global effort to find an effective vaccine within which the US is heavily involved.
As for your statement with regard to the AZ/Oxford programme "the US is paying for almost the entire thing" you are hugely overreaching.

ford family

Okay...well, a billion vs a couple hundred million...but fair enough.

 

[Jonfw2]

Every country is simply spending billions and billions to buy vaccines. The EU purchased and is getting 400 million doses of the AZ vaccine. Plenty of countries around the world are spending big, big money on vaccines. The U.S. is not unique in this regard.

We are a great spot to set up a vaccine trial though....so many infected people roaming around....which is not great, but hey, it is what it is right?

All fair points.

 

[aggiedog]

I don't know the exact indications for the monoclonal antibody treatment. I don't think it is simply the absence of antibodies without other clinical criteria - oxygen saturation, kidney function, sepsis, CNS involvement? I would assume you would have to have something on the moderate to severe side to be approved for an experimental treatment.

That the president got it doesn't really mean anything, as we have no idea what his real medical status is/was and I'd expect them to throw everything they had at him anyways to see what sticks.

 

[Jonfw2]

I don't know the exact indications for the monoclonal antibody treatment. I don't think it is simply the absence of antibodies without other clinical criteria - oxygen saturation, kidney function, sepsis, CNS involvement? I would assume you would have to have something on the moderate to severe side to be approved for an experimental treatment.

That the president got it doesn't really mean anything, as we have no idea what his real medical status is/was and I'd expect them to throw everything they had at him anyways to see what sticks.

Okay. So use the hospitalized as a starting point and determine which of them this might benefit.

 

[Cannot_Wait_4Disney]

I am curious who decides and what the deciding factors are on who gets this.

I'm not worried. The truly important people will be saved. Wait a minute. What do you mean that doesn't include me?

 

[aggiedog]

https://www.wired.com/story/trumps-miracle-cure-for-covid-is-a-logistical-nightmare/
Here's a good article that discusses why "the treatment will not cost anything" doesn't guarantee it won't cost anything, or even that you can get it. Not trying to argue, but more to say that there is theoretical "cost free" and there's the reality of implementation.

Some of it boils down even to our poor track record of testing. If you can't get test results back quickly, the window for treatment may be closed by the time you find out you're a candidate. Some is supplies (availability and cost) and where/who will do the infusion. Some is who decides who gets the first "free" 300,000 doses? Remdesivir turned out to have no uniform distribution or treatment priorities (which I already knew from hospital staff discussions.)