Yeah that stinks that Hairspray's gone, I didn't even know. Just read that it closed in January after I saw your post. Mamma Mia is still around, at least, and that one is also good for all ages. I've never seen Shrek, heard it isn't so great, but I'd assume that's family-oriented as well, lol. Wicked is supposed to be great, haven't seen it myself, but that's never been offered on TKTS because they run almost every show to full capacity. By the way, after I wrote my post I started looking up some other things and it sounds like the service in Mars 2112 has gone down pretty considerably since the last time I went. Still a cool place to check out once, but you might want to read some of those reviews, especially if you already had a bunch of other places in mind. I've been to Katz's only once and it was probably almost 15 years ago so I wouldn't want to comment on that (but everyone does say it's great).
As far as neighborhoods go, as long as you're hitting up touristy spots like museums, Central Park, 5th Ave, Times Square, etc., you won't find yourself in any ridiculously bad areas so I wouldn't even worry about it. I forgot to mention that if you do wind up shopping on 5th Ave, check out the Apple Store, it's really cool (even if you're just passing by).
As far as neighborhoods go, as long as you're hitting up touristy spots like museums, Central Park, 5th Ave, Times Square, etc., you won't find yourself in any ridiculously bad areas so I wouldn't even worry about it. I forgot to mention that if you do wind up shopping on 5th Ave, check out the Apple Store, it's really cool (even if you're just passing by).