To add, my favorite characters on Bob's are:
Louise - though they have softened her a bit. I love her attitude! In a very early one where they are considering renting their apartment as a BNB, Linda want's or offer Louise's room, and Bob in a very deadpan manner says, "No, not Louise's room. She will murder us."
Galye - Oh, my, what is wrong with this woman? I mean, Linda's pretty nuts, but Bob definitely got the better of the sisters! But, man, Gayle is hillarious, from her cats, to her made up board games - dare you face the "Gayle Force Winds" - She cracks me up!
Mr. Fischoeder - The resident rich lunatic, I guess he's slightly nicer than Mister Burns! He's very funny, especially when he is negotiating some kind of scam with Louise!
Zeke - This kid so nuts - I love his energy. He seems like a "bad" kid but is actually really good natured, though a little hyper-active. He and Jimmy Jr. make a good team!
And, of course...
Bob - Patricularly when he is talking to the food he is cooking or a Thanksgiving turkey, this dude has lost his mind. He's pretty out there, and yet somehow he's still the voice of reason in the family. I love when he is trapped in the wall and is hallucinating the Kuchi Kopi toy as a bartender! "They all hate you, Mister Bob."