We're renting a home through VRBO next month. At first I was going to go through an agency (closesttodisney.com), but wasn't happy with the service. When I made the reservation with them, I got an e-mail that was actually kind of vague and had no confirmation number. When I e-mailed them with more questions, all I got back was a blank e-mail with their company letterhead at the top. Two attempts to call them were greeted by an answering machine, and no returned calls.
After this I decided, after reading positive posts here, to go through VRBO. It took me a couple of hours to find a nice house, in a decent location, at a price that was within our budget. I received a confirmation e-mail the next day from the owner. When I e-mailed with more questions, he replied promptly. He didn't hesitate to give me his home and cell phone numbers, and his home address. He also had good feedback at VRBO. I sent payment in the form of a cashiers check, and he let me know as soon as it arrived.
When we get back (April 25th) I plan to post a trip report, but will also post on this board and let everyone know how the experience was in regards to the rental home.