He needs to get loud and agressive regarding Obama's past.
What's his association with ACORN? (specifics please)
What's his association with Ayers? (specifics)
What's his association with Odinga and the Orange Democratic movement?
I'm sure there are many more great questions that need to be answered.
McCain needs to address all of those questions. People will care about Ayers when they see the depth of the relationship that Obama has denied. What is more important than why Obama likes Ayers is why Ayers likes Obama. What does he see in him that will advance his agenda? He needs to focus on ACORN as well. He is about to have the election stolen because of the fraud that has permeated each and every state. His meddling in Kenyan politics is very concerning. That needs to be discussed. The Washington Times came out with another article today about Obama secretly trying to meddle in the troop strength in Iraq. That needs to be looked at. Friendships with Rezko, how he benefited as well as Rashid Khalidi need to be looked at.
I think that McCain would do well to repeat what he said yesterday, investigations of those who caused the Fannie Mae/Freddie Mac melt down. He named Dodd, Obama and Frank yesterday. He promised investigations. He should name Rudy Giuliani as his AG. Mitt Romney as Treasury Sec'ty for starters.

If Americans aren't offended by Ayers, lets look at his wife!