I had no problems until several days before getting mine out. I woke up around 2-3 in the morning a couple nights in a row, with pains in my stomach. They lasted about an hour. Went back to bed, went to work the next day...I was fine. The next night, same thing...about an hour later, the pains went away and I went back to sleep, went to work...I was fine. The third night, the pains were more severe and went around to my back. This time, they weren't going away. I ended up waking my husband up and telling him he had to take me to the hospital. After some tests, they determined that my gall bladder was loaded with stones and had to come out, ASAP. I ended up being admitted and had the surgery two days later. Good luck!