First Get a couple Shop Your Way (SYW) cards. These cards come out with amazing offers and all the offers stack which makes this card absolutely mind blowing. You can easily profit upwards of $3k off this one card per year per card. Couple this card with Fluz for the bonus categories to truly maximize it.
Then you can sign up for Amex biz cards every 90 days Biz Plat and Biz Gold. Just make sure they have no lifetime language (NLL) or else Amex will deny you the sign up bonus (SUB) But recently the offers on the Plat was 250k MR and the Gold was 200k. That's 450k Membership Rewards. Sell those for a minimum of $0.0125/point for $5,625. This can be repeated every 90 days. Wife does the same.
This is just a VERY small example of what I'm doing in the miles/points game. This is only a little of what I'm doing geared towards
DVC.