There really are no bad rooms at the GF, with the possible exception of the 2nd floor rooms that overlook the port cochere. Do you prefer high floor or low floor? I would ask for that. Would you prefer a view of the monorail, wedding pavilion, golf course, and Poly? Or would you prefer a view of the Grand Floridian main building, with the monorail off to the left?
Personally, I prefer the view of the GF main building, but last time I stayed, I arrived early and they had a room ready for me on the golf course side. It was a great room. I still prefer the other side, but i am totally happy if I get the other view. I just make sure to ask for a high floor.
There are three very fast elevators at VGF, so requesting a high floor does not slow you down.