So, my boys do not like Disney. Quite honestly, my husband would rather not go. So we now make a point to go to various cities each year. Since deciding to visit at least one new city a year we have been to:
Niagara Falls, Ontario (meet some of DH family here)
Las Vegas (took the teens)
Baltimore Harbor (Just me and DD stopped there when traveling to/from her cheer camp in PA)
Austin, TX / San Antonio, TX (DS and DH went for a convention DH wanted to go to)
Washington, DC (on the way home from Niagara Falls
We have been to many more cities but those are just in the last couple years. I think Niagara Falls was a nice quiet family vacation that is good for multiple generations traveling together.
Las Vegas was pretty awesome and we may go back there next year with some close friends. We definitely didn't come close to doing and seeing everything. Neither DH or I gambled at all. DH says he wished he would have just played one hand. LOL. Maybe next time.
One of our other favorite family vacations was near Boone, NC where we renting a cabin and went to a couple ski resorts there over MLK weekend. We have never been to any other ski resorts so this was our first and only time at a ski resort. This was also good for multiple generations. The grandparents watched the kids snow tubing, etc. then went to the cabin to prepare dinner. The family played board games in the cabin near a big huge window watching the snow fall.
I think visiting different parts of the country is a great vacation. My kids can say they have been to all these different places. I find it is educational as well.