The Walt Disney Family Museum is in San Francisco, if I'm remembering correctly.
I've also done a bike tour of La Jolla before and that was amazing.
The Walt Disney Family Museum is indeed in San Francisco (Presidio) and is an incredible experience although I wouldn't go with small children (under 8). It's A LOT of information and not so much hands on or entertaining (for a child any way) like you'd think with it being Disney. But it is a wonderful, wonderful museum for older children and especially adults. It is great for everyone - not just Disney fans! If you do go, plan for a minimum of 3 hours but you could realistically spend 4-5 hours if you take your time through it all.
You should 100% visit Hearst Castle. It's a beautiful place to visit. Last time we ventured up that way we did an Air B&B in Cambria for a few days but not necessary to spend that much time there.
There's a billion things to do in L.A. if you plan to visit there. The Getty Center is a popular site among the locals. Of course Hollywood and the Hollywood Sign. Olvera Street is a cute little authentic Mexican village located across the street from L.A. Union Station and a block away is Philippe's the Original (Famous for their French Dipped sandwich of which I've consumed about 300 of in my lifetime

- 5 generations of my family have enjoyed those sandwiches!). You might be interested in a tour of Dodger Stadium as it is a pretty historical spot for sport's fans or not. All of that from Olvera Street to Dodger Stadium are located within about 3 miles of each other.
Santa Monica (west of L.A.) has a famous pier with lots of fun things to do.
Of course you have Universal Studios just north of L.A. but if you have experienced USO you may not be too thrilled with our's. Knott's Berry Farm is a miss for me. But please, please do
Disneyland if it's not already on your list. There is just something special about it. I love WDW but something about Disneyland is just very charming and unique.
Orange County, other than Disneyland doesn't have much more to offer. Although, I do love the Huntington Beach pier and the fire pits on a nice evening to enjoy the sunset and roast mallows

It's our go-to, local beach. Another fun spot is Balboa Island in Newport Beach, just south of Huntington. We like to take the ferry - my kids get a kick out of the 5 minute ride

They have cute little shops and restaurants and it's just nice to walk along the sea wall at sunset or rent a bike. You can also rent duffys and such there or perhaps ride the ferris wheel.
Then San Diego has lots as many have already mentioned. The San Diego Zoo is world famous. I also enjoy the Safari Park. Sea World is there as is
Legoland (Carlsbad) but I loathe Legoland and would not recommend it unless you have really small children. (Even then it's excruciating for me to go

)
That's about all I can think of right now but would be happy to answer any questions!