There will definitely be a major recession, and soon (within the next couple years).
One major indicator has been home sales in typically hot markets like Southern CA. Home sales have fallen the last couple quarters and the experts say that this may be a huge warning sign for the rest of the country as a whole. When the hot real estate markets start stagnating, it's a bad sign. Of course, it is just one indicator, but it has held up as an accurate predictor for the past several recessions.
No one has any idea when the next major recession will happen. Anyone who claims they can predict is probably trying to sell you a book or financial services.