At the top is the airport location for
Avis.
The lower one is closest to the
Disney cruise terminal and hotels you were considering. (Kettner Ave).
You will also pay for parking at the hotel.
Are you planning on going out in San Diego? Or just need to have a vehicle (I understand). Otherwise, hotel shuttle from the airport. Eat within walking distance and then walk or rideshare to the port is actually less transfers / time / money (probably than a car rental).
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Car rental with drop-off at Kettner is actually cheaper than return at airport ($199) for the shown date.
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