I don't think there's a bad building at POFQ. We just got back from spending 2 weeks there and loved it so much that we have shelved our original plans for next year at different resorts to go back there. I spent a lot of time on the link Wayne gave you and as he says, it's a great source of information with some gorgeous pictures too.
We stayed in Building 5 and were very happy with our room location. If you book a river view there will be some buildings you won't be in - for example 1 and 4 do not have water views but are very close to the main buildings. However as already mentioned by others, you won't be far from anything wherever you stay there.