No holidays during those two weeks in the US that I can think of.... Columbus Day causes quite a crowd but that's about half way through the month of October. We are actually planning our trip for the last week in Sept, coming home on Sept 30th. If it matters to you - the only thing that I found a benefit for the 1st week in October is the fact that the Mickey's Not So Scary Halloween Party starts on Sept 30th, so we're actually missing it. I don't know if I would've planned my trip around it anyway, but it might have been neat to see what the fuss is all about! Good luck with your decision! Also - I don't think one week will make a diff in weather, but isn't Sept generally wetter?