Make a list of the amenities that are most important to you. Then eliminate any resorts that don't have those amenities. That should help narrow down the list considerably. Only you know what will make or break a vacation for your family.
Once you have your short list, think about which parks you will spend the most time in. Are any of the resorts on the short list closer to those parks than the others, maybe even walking distance? Will you have direct transportation to your favorite parks, or will you be sharing with other resorts? Is there more than one form of transportation available?
Do you need separate sleeping areas for adults and kids? For some families, it's OK to be all together in one smallish room at a value, but for others, having adult space is very important. With the family suites at the values, the FW cabins, and the
DVC villas, you can get extra space if you need it.
Also, which theme appeals to you the most. I live in Florida, so I prefer the themes that are least like Florida (WL is a particular favorite of mine). If you live up north, perhaps you are looking for a tropical vibe, or an African vibe, or a southwestern vibe. Some people want their vacation to be very "Disney", i.e., lots of Mickey and the gang all over the place, and others want a more subtle theme that lets them leave the theme parks behind at the end of the day and relax.
As far as your budget goes, consider whether you want to spend more on the resort, or more on other activities. There isn't a right or wrong answer. Some people look at the room as just a place to sleep and shower between the fun in the parks. Some people spend as much time at the resort as they do in the parks so the resort and it's amenities are more important. You can do a lot of shopping and higher end dining on the difference between a value and a deluxe. But if you plan to spend a lot of down time at the resort, having recreational amenities and a well themed pool could be more important than meeting Mickey at dinner.
The only way you can make a wrong decision is if you base your decision on what everyone else says instead of thinking about your family and their needs. What makes a vacation perfect for me isn't necessarily what makes a vacation perfect for you. Lots of people love AKL and it's my least favorite deluxe. I love CR, and a lot of people don't think it has much theming at all. Everyone is different, and only you know what will make your family happy.