The best info I have is to try to make it to North Carolina or South Carolina the first day. Second day will only be an 8-hour trip to Orlando. I did this in April, with only two drivers. (going again in two weeks!) We left at 6 a.m. on a weekday, and arrived just over the border of South Carolina at 11 p.m. We pulled off the road and stayed at a Comfort Inn. We started off again the next morning at 8 a.m. and arrived at Disney's Animal Kingdom Lodge at 3 p.m. Satruday on the dot. We had two teens, and a 4 year old with us, and we stopped along the way for breaks. There is an alternate route other than 95 South which avoids NYC, and Washington, it's I-84 West to I-81 south to I-77 South to I-26 East to I-95 South to I-4 south to Orando. A friend of mine Did this in 14 hours the first day, stopped at Rock Hill, SC overnight, and continued 8 more hours the second day. the return trip was even faster, 12 hours, stopping at Harrisonburg, VA, and then another 8 hours the second day. I hope this helps. Have a safe trip!!!