Driving in the LA area isn't that bad. I FAR prefer it to driving in places like Atlanta or Orlando, where for me it's just misery. Use Waze, pay attention to traffic, try to avoid obvious rush hour times if possible, and you're golden. It's not scenic, and you'll probably be sent from this highway to that, but it's very very doable.
I will say that dealing with LAX can be a pain. If you've ever dealt with any major airport, you probably have a fair idea of what to expect, but there are some unique wrinkles to this particular airport. People getting off the plane at LAX have NO urgency whatsoever, and it can take quite a lot of time to get off the plane, get your baggage, wait for the rental car shuttle, get out of the terminal complex on the shuttle, get to the rental car lot, get the car, etc. Do not underestimate the amount of time it will take to leave LAX in any scenario, and don't forget to budget for yourself plenty of time to get from DLR to LAX when you're heading back, and don't forget to add time to take the shuttle back to the terminal after you return your rental car.