We live in northern NJ (Bergen County) and have driven down a few times. We like to drive straight through with a majority of the driving done during the night however, we have stayed over. We have stayed at the Country Inn & Suites in Santee, SC. It's a nice clean hotel with friendly staff and a free breakfast for a little under $100 a night. It also has an indoor pool. It took us 12 hours to get to Santee, SC but, that was with stopping for a sit down breakfast and a sit down lunch, plus gas/potty breaks and 20 minute stop on the side of I95 while I cleaned up vomit from the back seat.