CDC Notifies States, Large Cities To Prepare For Vaccine Distribution As Soon As Late October

[DLgal]

Yes...just listening to the news and the Moderna vaccine doesn't need to be kept as cold, and can be kept at refrigeration for a number of hours...I think 36, and can even be kept at room temperature for up to 12 hours. That's a big deal.

The Pfizer vaccine only starts to break down after 10 DAYS out of its super cold storage. So, I don't think it is going to be as big an issue as it's being made out to be.

 

[dvcgirl67]

The Pfizer vaccine only starts to break down after 10 DAYS out of its super cold storage. So, I don't think it is going to be as big an issue as it's being made out to be.

I've read that the Pfizer vaccine can last 10 days in the special containers Pfizer has built for transport. And then up to 5 days in a regular fridge, I guess as it's thawing. After all we've been through I'd like to know that I'm getting a vaccine that was thawed that day. I don't want to get that Pfizer vaccine if it's been in fridge for 5 days....kind of like buying chicken on the sell-by date.

 

[LuvOrlando]

https://www.frontiersin.org/articles/10.3389/fimmu.2019.00594/fullSo these have been in the works for a while, maybe not launched full scale but it's not like they were just dreamt up in March 2020 and being tossed into the fray fingers crossed, it's more likely the mainstream world just wasn't paying any attention.

Came back to say that when I research a thing I tend to like to go back in time a bit to before an idea became part of the machine, so to speak. Information is so much more useful before it's whitewashed & distorted and so I dig & I dig, but always backwards then I grab a few ideas and move on my own path.

 

[okeydokey]

I would love to see large scale distribution by end of Spring!!!

I for one will absolutely get the vaccine. My husband and adult children will as well.

 

[Jonfw2]

Moderna’s CEO says every American who wants to be will be vaccinated by June.

Numbers should start plummeting long before that as more and more are vaccinated over time.

 

[crazyventures]

This is encouraging news! I had a baby 3 weeks after my area issued its Shelter-in-Place order and we've been very cautious for these past 8 months. Hopefully the next month brings some more good news re: FDA approval and an estimated timeline for distribution of any potential vaccines. Definitely going to remain careful due to rising case numbers and strained hospital systems in many parts of the country.

 

[Colleen27]

The Moderna news is excellent. Actually better, in my mind, than the Pfizer news in that the Moderna is much easier to transport and store, so will be easier to distribute along normal channels.

I agree. The Moderna announcement is good news on two fronts - having a second successful vaccine will make the effort to produce billions of doses that much more viable, and having one that is more easily stored and transported makes distribution much simpler.

I can definitely speak on that. When we were first interviewed for the Moderna trial, they made it very clear that while they could not force us to go out and do stuff, it was very, very helpful if we did. They asked us a number of questions regarding our potential exposure. My wife and I have a daughter in every day in person school and I go to the gym. So we were in. If we had told them that we were sitting in the basement all day, they would have rejected us from the study.

I personally didn't apply, but this is similar to what I've heard from a friend who is in a local trial (not sure of which vaccine) - she was accepted in part because she's an essential retail worker and therefore likely to be exposed to the virus. Her sister, who is currently a SAHM, was rejected because she's so well isolated that her exposure risk didn't meet the minimum threshold.

The "new" team will work just fine with Birx and Fauchi as well as others.
These are all seasoned folks in the areas of epidemiology, public health and government. They know each other. They respect one another.
They understand the mission.

And it isn't as though the new team is intended as a replacement. Fauci and Birx will still be there come Jan. 21 - they just cannot, as current federal employees, be part of the transition task force.

 

[Jonfw2]

Someone had asked last week about Pfizer’s supply chain capacity- they can ship 7.4 million units per day from their factory to the airport.

 

[bethbuchall]

The Moderna news is excellent. Actually better, in my mind, than the Pfizer news in that the Moderna is much easier to transport and store, so will be easier to distribute along normal channels.

The one thing I’d still love to know with these studies is, how are the people that are participating in it behaving once they’ve received the injection? Are they still in full on quarantine, are they going out only briefly with masks on, or are they all going out with no mask as often as possible? Because the results would be quite skewed if a large majority of the 15k that received the actual vaccine were still in a lockdown situation. I wish we knew more on this.

My husband and I are in the Pfizer study. At the initial visit, we were asked how often we were exposed to other people in order to determine if we were good candidates. Although we don't go out a lot, since my husband can primarily work from home and the preschool where I work is closed, I do go out to the grocery store once a week. We also see our adult children (one does not work from home) maybe once a month and will have our college son back home at the end of the semester. That was enough. We aren't living any differently than we would if we weren't in the study nor would we if we were sure that we were given the vaccine. We are both reasonably certain that we received placebo, though we don't know anything officially (yet).

Thanks - I was too slow getting the question posted.
ETA: was there any discussion of making it a “challenge-trial” and if so, would you have participated?

I personally would not have done a "challenge-trial" at my age and with possible other complications. I want to help, but I need to feel comfortable with the risks.

 

[Ariel484]

Pfizer is starting a pilot delivery program:
https://www.reuters.com/article/us-...immunization-in-four-u-s-states-idUSKBN27X09A

 

[goofyernmost]

My God- you are rolling strikes today. Absolutely correct again.

And I think we agree that while many will still be fearful at first, there are enough who will not be to make this work.

I would have volunteered because my immune system has been described as very strong. However, I am 72 and have COPD so I am high risk. I would be in line as long as I know that it is the real vaccine and that I wouldn't end up with a placebo. I can't afford to do that without feeling that if it works I will be ok. I don't have the kind of time to play Russian roulette with it.

 

[Jonfw2]

I would have volunteered because my immune system has been described as very strong. However, I am 72 and have COPD so I am high risk. I would be in line as long as I know that it is the real vaccine and that I wouldn't end up with a placebo. I can't afford to do that without feeling that if it works I will be ok. I don't have the kind of time to play Russian roulette with it.

I hope you’re first in line!

 

[wenrob]

So I read this today. It talks about using the “acquaintance method” for distributing vaccines. Basically it would be healthcare workers first (who actually fall into that category) and then you would target potential Super Spreaders to cut off the “hubs” for the virus. They gave an example of three people and asked for acquaintances. Two named the same guy, so they both know him but don’t know each other. He’s the one who gets the vaccine because he’s the one who is the social butterfly. Another example was a party guy who never uses a mask and his grandma who doesn’t really go anywhere. Who gets it? Your instinct is grandma but if you give it to party dude it protects not only him but grandma and others because it stops him from spreading the virus because he’s reckless. With just giving it to grandma it kind of stops there but party dude it breaks a chain of transmission. The idea is this method would only need 20% vaccinated to bring the virus to heel. Wouldn’t get rid of it but it would block its path. Ethically at the end of the day they feel it’s appropriate to vaccinate the vulnerable first. Anyway, I thought is was really interesting and might add to the conversation.
https://apple.news/AmMjzLCfYS0ahVJpwVH3HdA

 

[Jonfw2]

95% efficacy. 94% for the elderly.


Pfizer says Covid vaccine is 95% effective – plans to submit to FDA in 'days'
https://www.cnbc.com/2020/11/18/cor...are|com.apple.UIKit.activity.CopyToPasteboard

 

[dvcgirl67]

Good news. Pfizer completes trial, says vaccine has 95% efficacy. Can have 50 million doses available by the end of the year, 25 million of those doses for the United States, enough to vaccinate 12.5 million Americans. Will apply for Emergency Use Authorization from the F.D.A within days.


https://www.nytimes.com/2020/11/18/health/pfizer-covid-vaccine.html?smid=tw-nytimes&smtyp=cur

 

[dvcgirl67]

95% efficacy. 94% for the elderly.


Pfizer says Covid vaccine is 95% effective – plans to submit to FDA in 'days'
https://www.cnbc.com/2020/11/18/coronavirus-pfizer-vaccine-is-95percent-effective-plans-to-submit-to-fda-in-days.html?__source=iosappshare|com.apple.UIKit.activity.CopyToPasteboard

Ha...you beat me by a minute!

 

[dvcgirl67]

95% efficacy. 94% for the elderly.


Pfizer says Covid vaccine is 95% effective – plans to submit to FDA in 'days'
https://www.cnbc.com/2020/11/18/coronavirus-pfizer-vaccine-is-95percent-effective-plans-to-submit-to-fda-in-days.html?__source=iosappshare|com.apple.UIKit.activity.CopyToPasteboard

I sincerely hope that the healthcare workers at long term care facilities are first on the list. Residents at long term care facilities are 1% of the U.S. Population, but make up over *40%* of all Covid deaths. They don't leave those facilities, and many are still not allowing visitors, so the virus is coming in from the people who work there. That would have a huge impact very quickly.

 

[Jonfw2]

I sincerely hope that the healthcare workers at long term care facilities are first on the list. Residents at long term care facilities are 1% of the U.S. Population, but make up over *40%* of all Covid deaths. They don't leave those facilities, and many are still not allowing visitors, so the virus is coming in from the people who work there. That would have a huge impact very quickly.

From what I’ve heard, Pfizer’s logistic tests have been specifically focused on getting the “suitcases” from the facility to the airport to the truck to a nursing home.

 

[dvcgirl67]

From what I’ve heard, Pfizer’s logistic tests have been specifically focused on getting the “suitcases” from the facility to the airport to the truck to a nursing home.

That would be amazing. So many lives will be saved by getting a "vaccination fence" around those nursing homes. It would just be a huge, huge deal.

 

[Jonfw2]

That would be amazing. So many lives will be saved by getting a "vaccination fence" around those nursing homes. It would just be a huge, huge deal.

yes. This is where you get plummeting hospitalizations and even more plummeting death rates.