Clearly the best way BY FAR is to come down I75 to the turnpike and follow the 'Pike to exit 267a (I think it's 'a'). Anyway it will take you to another toll road Hwy 429 which goes south (the ramp pulls off and bear to the right). There's one toll booth as I recall and get off at exit 6 or 8 (can't recall) and the exit is for "Western Way". This route is lightly travelled and is especially nice if you are towing or pulling anything. It comes into the Disney property by Coronado Springs Resort and Blizzard Beach.
It beats coming in on Hwy 535 (too many subdivisions, two lane road, and traffic) and it sure as heck beats taking the 'Pike to I4. You will love taking 429.
Watch out on the Western Way itself - it can be a speed trap and is frequently patrolled so watch your speed!
Enjoy!
Bama ED