My nephew has Asperger's. We took him in March of last year. Since this was his first time, it was definitely a learn as you go sort of process. Toward the middle of our trip we figured out that it was best to stay around the resort and let him swim for the biggest part of the day. We toured the parks in the evening when it wasn't so hot and it was less crowded. We also learned to let him call the shots. Meaning, when he was ready to go back to the resort, we went. When he found a ride that he really liked and wanted to ride it over and over, we rode it over and over. The trip was about him..not us. Of course, every individual with Asperger's is different. So what worked for us may not work for your friend's daughter. I can tell you that all of the CMs we came in contact with were excellent. I believe there are some threads on here discussing special needs such as Asperger's and Autism. Check out Mom's Panel and Allears, as well. We found all of these to be great sources of information and so helpful in planning our trip. Just know that things will probably not always go as planned. Good luck! Disney is a magical place and our nephew is still talking about the memories he made!