I'm not an expert, but I do know a lot about Florida travel.
An impotant note: If you are coming South on I-95, and going West on I-4, you will NOT want to go through Orlando at these times. 7:30am-9:00am, 11:00am-1:00pm, or 4:30pm-7:00pm. I know that doesn leave much, but its better than waiting an hour in an area that you should be out of in 20 minutes.
I-4 is not the best place, as many areas of it are under construction.
As for I-10 in Pensacola, I have no clue what is going on there.
I-75 isn't too bad a route either.
I have never traveled the Florida Turnpike, so I can't help you there.
You may want to try
http://www.baynews9.com and click TRAFFIC and look up I-4, but I don't know how much help that will give you.
Thats all the help I could give.
(Check out my other post of Fav Rides)