Back when we used to drive to Disney, 1200 miles one way, I used to drive straight through my self. Never let wife drive. We're talking 30 some years ago and there were a heck of alot less things on the road. We tried a driving trip a few years ago and even took the longer route from out home and it was a nightmare. Finally let the wife drive, we're in our 50's now, and she did the first stint and when she said it was my turn, around 9 pm, I said find a motel. Too many trucks on the road for me and they seem to gang up in the night, long convoys, and fly along.
I used to enjoy the drive but it has become to stressful with all the traffic and inconsiderate drivers on the road. Even stopping for the night doesn't help, day drivers are going to work and hopping on and off the super highways like bugs. You always have to be alert, and being alert for 20 some hours over 1200 miles of super highways is very tough and stressful. Night time used to be the best, get behind one semi and just go with the flow, used to be just us on the road and no one else. Also, the older you get, the harder it seems to see in the dark, not saying we're old but it isn't the same as when we were in our 30's.