Hi Kirsty,
I lived in San Jose for 22 years which is about 40 minutes south of San Fran. There's lots to see and do in the area! It is about a 7 hour drive to
Disneyland. In San Francisco I can think of the following to do:
Pier 39 and Fisherman's Wharf. Lots of shopping and kitchy entertainment. From Pier 41 you can take a ferry and take a tour of Alcatraz Island. Get a chowder bowl at Boudin's Bakery---yummy. Their tuna sandwiches are great too.
Drive around Nob Hill and Lombard street
Have a picnic at Golden Gate park
Catch a Giants game at their new stadium (very close to Pier 39)
Shop in Union Square
Eat some chocolate at Gharadelli Square
Go to the Science Museum- it's called the Exploratorium
The San Francisco Zoo is decent
You can go north to Napa area for a day and explore wine country or visit a spa in Calistoga
East to Vallejo and go to Marine World USA (a six flags park)
Go South to Santa Clara and go to Paramounts Great America
Go further South and go to the beach at Santa Cruz and take a ride on the Giant Dipper wooden roller coaster
It's a very beautiful area!! If it weren't for the CRAZY housing prices, I would probably still live there.